Publications

Scientific research is always ongoing at Micropathology Ltd. See some of the publications we're involved in below.

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Plasma Protein Biomarkers Distinguish Multisystem Inflammatory Syndrome in Children From Other Pediatric Infectious and Inflammatory Diseases.
Yeoh S, Estrada-Rivadeneyra D, Jackson H, Keren I, Galassini R, Cooray S, Shah P, Agyeman P, Basmaci R, Carrol E, Emonts M, Fink C, Kuijpers T, Martinon-Torres F, Mommert-Tripon M, Paulus S, Pokorn M, Rojo P, Romani L, Schlapbach L, Schweintzger N, Shen C-F, Tsolia M, Usuf E, van der Flier M, Vermont C, von Both U, Yeung S, Zavadska D, Coin L, Cunnington A, Herberg J, Levin M, Kaforou M, Hamilton S, PERFORM, DIAMONDS and UK KD Genetic Consortia close, 2024 Pediatr Infect Dis J
Archives of Disease in Childhood: 2024 Vol: 109: 1 pp: 58-66

External validation of a multivariable prediction model for identification of pneumonia and other serious bacterial infections in febrile immunocompromised children
Martin AJ, Van Der Velden FJS, Von Both U, Tsolia MN, Zenz W, Sagmeister M, Vermont C, De Vries G, Kolberg L, Lim E, Pokorn M, Zavadska D, Martinon-Torres F, Rivero-Calle I, Hagedoorn NN, Usuf E, Schlapbach L, Kuijpers TW, Pollard AJ, Yeung S, Fink C, Voice M, Carrol E, Agyeman PKA, Khanijau A, Paulus S, De T, Herberg JA, Levin M, Van Der Flier M, De Groot R, Nijman R, Emonts M
Archives of Disease in Childhood: 2024 Vol: 109: 1 pp: 58-66

A multi-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children (PERFORM): a multi-cohort machine learning study
Heather R Jackson*, Judith Zandstra*, Stephanie Menikou, Melissa Shea Hamilton, Andrew J McArdle, Roman Fischer, Adam M Thorne, Honglei Huang, Michael W Tanck, Machiel H Jansen, Tisham De, Philipp K A Agyeman, Ulrich Von Both, Enitan D Carrol, Marieke Emonts, Irini Eleftheriou, Michiel Van der Flier, Colin Fink, Jolein Gloerich, Ronald De Groot, Henriette A Moll, Marko Pokorn, Andrew J Pollard, Luregn J Schlapbach, Maria N Tsolia, Effua Usuf, Victoria J Wright, Shunmay Yeung, Dace Zavadska, Werner Zenz, Lachlan J M Coin, Climent Casals-Pascual, Aubrey J Cunnington, Federico Martinon-Torres, Jethro A Herberg, Marien I de Jonge†, Michael Levin†, Taco W Kuijpers†, Myrsini Kaforou†, on behalf of the PERFORM consortium‡
Lancet Digital Health: 2023,:Vol 5: 11 pp e774–785

Diagnosis of childhood febrile illness using a multi-class blood RNA molecular signature
Dominic Habgood-Coote 1, Clare Wilson 1, Chisato Shimizu 2, Anouk M Barendregt 3, Ria Philipsen 4, Rachel Galassini 1, Irene Rivero Calle 5, Lesley Workman 6, Philipp K A Agyeman 7, Gerben Ferwerda 4, Suzanne T Anderson 8, J Merlijn van den Berg 3, Marieke Emonts 9, Enitan D Carrol 10, Colin G Fink 11, Ronald de Groot 4, Martin L Hibberd 12, John Kanegaye 2, Mark P Nicol 13, Stéphane Paulus 14, Andrew J Pollard 15, Antonio Salas 16, Fatou Secka 8, Luregn J Schlapbach 17, Adriana H Tremoulet 2, Michael Walther 8, Werner Zenz 18;
Med. 2023 Sep 8;4(9):635-654.e5.

Febrile illness in high-risk children: a prospective, international observational study
Fabian J S van der Velden,Gabriella de Vries, Alexander Martin, Emma Lim , Ulrich von Both, Laura Kolberg, Enitan D Carrol, Aakash Khanijau , Jethro A Herberg, Tisham De, Rachel Galassini, Taco W Kuijpers, Federico Martinón-Torres, Irene Rivero-Calle, Clementien L Vermont, Nienke N Hagedoorn , Marko Pokorn , Andrew J Pollard, Luregn J Schlapbach, Maria Tsolia, Irini Elefhteriou, Shunmay Yeung, Dace Zavadska , Colin Fink, Marie Voice, Werner Zenz , Benno Kohlmaier , Philipp K A Agyeman , Effua Usuf, Fatou Secka, Ronald de Groot, Michael Levin, Michiel van der Flier, Marieke Emonts ; PERFORM consortium
European Journal of Pediatrics, 2023 Feb;182(2):543-554.
https://doi.org/10.1007/s00431-022-04642-1

Genomic investigations of unexplained acute hepatitis in children
Sofia Morfopoulou, Sarah Buddle, Oscar Enrique Torres Montaguth, Nathaniel Storey, Laura Atkinson, José Afonso Guerra-Assunção , Sunando Roy, Alexander Lennon, Jack C D Lee, Rachel Williams, Charlotte A Williams, Helena Tutill, Nadua Bayzid, Luz Marina Martin Bernal, Catherine Moore, Kate Templeton, Claire Neill, Matt Holden, Priyen Shah, Samantha Coorey, Marie Voice, Michael Steele, Colin Fink, Thomas E Whittaker, Giorgia Santilli, Paul Gissen, Simon N Waddington, Juan Diaz, Thomas S Jacques, Chayarani Kelgeri, Rachel Brown, DIAMONDS and PERFORM consortia, James Hatcher, Surjo De, Glenn Anderson, Eileen Gallagher, Ruth Simmons, Conall Watson, Sema Mandal, Julien Andreani, Peter Simmonds, Maria Zambon, Meera Chand, Luis Campos, Joanne Martin, Emma Thomson, Michael Levin, Ines Ushiro-Lumb, Julianne R Brown, Judith Breuer
Nature volume 617, pages 564–573 (2023)
https://doi.org/10.1038/s41586-023-06003-w

Low levels of factor H family proteins during meningococcal disease indicate systemic processes rather than specific depletion by Neisseria meningitidis.
van Beek, Anna E, Pouw, Richard B, Wright, Victoria J, Sallah, Neneh, Inwald, David, Hoggart, Clive, Brouwer, Mieke C, Galassini, Rachel, Thomas, John, Calvo-Bado, Leo A, Fink, Colin, Jongerius, Ilse, Hibberd, Martin, Wouters, Diana, Levin, Michael and Kuijpers, Taco W on behalf of the EUCLIDS Consortium
Frontiers in Immunology, 13-2022.
https://doi.org/10.3389/fimmu.2022.876776 ISSN 1664-3224.

Variation in CFHR3 determines susceptibility to meningococcal disease by controlling factor H concentrations
Vikrant Kumar, Richard B. Pouw, Matias I. Autio, Manfred G. Sagmeister, Zai Yang Phua, Lisa Borghini, Victoria J. Wright, Clive Hoggart, Bangfen Pan, Antson Kiat Yee Tan, Alexander Binder, Mieke C. Brouwer, Ellie Pinnock, Ronald De Groot, Jan Hazelzet, Marieke Emonts, Michiel Van Der Flier, Karl Reiter, Markus M. Nöthen, Per Hoffmann, EUCLIDS consortium, Luregn J. Schlapbach, Evangelos Bellos, Suzanne Anderson, Fatou Secka, Federico Martinón-Torres, Antonio Salas, Colin Fink, Enitan D. Carrol, Andrew J. Pollard, Lachlan J. Coin, Werner Zenz, Diana Wouters, Lay Teng Ang, Martin L. Hibberd, Michael Levin, Taco W. Kuijpers, and Sonia Davila,
American Journal of Human Genetics. 2022 Sep 1; 109(9): 1680–1691.
https://doi.org/10.1016/j.ajhg.2022.08.001 ISSN 0002-9297

Diagnostic accuracy of multiplex respiratory pathogen panels for influenza or respiratory syncytial virus infections: systematic review and meta-analysis.
Sophie Jullien, Felicity Fitzgerald, Suzanne Keddie, Oliver Baerenbold, Quique Bassat, John Bradley, Jane Falconer, Colin Fink, Ruth Keogh, Heidi Hopkins and Marie Voice
BMC Infectious Diseases (2022) 22:785
https://doi.org/10.1186/s12879-022-07766-9

Circadian rhythms in the plant host influence rhythmicity of rhizosphere microbiota
Amy Newman, Emma Picot, Sian Davies, Sally Hilton, Isabelle A. Carré and Gary D. Bending.
BMC Biol 20, 235 (2022).
https://doi.org/10.1186/s12915-022-01430-z
https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-022-01430-z

Comparing lateral flow testing with a rapid RT-PCR method for SARS-CoV-2 detection in the United Kingdom - A retrospective diagnostic accuracy study.
Taylor A, Calvez R, Atkins M, Fink CG.
Health Sci Rep. 2022;5:e811. doi:10.1002/hsr2.811.
https://onlinelibrary.wiley.com/doi/10.1002/hsr2.811

The temporal pattern and lifestyle associations of respiratory virus infection in a cohort study spanning the first two years of life.
Powell E, Sumner E, Shaw AG, Calvez R, Fink CG, Kroll JS.
BMC Pediatr. 2022 Mar 31;22(1):166. doi: 10.1186/s12887-022-03215-3.PMID: 35361147
https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887-022-03215-3

Treponema pallidum PCR testing for diagnosis of mucocutaneous ulcers suspicious for syphilis.
Muhammad Hyder Junejo, Mark Collery, Gary Whitlock, Alan McOwan, Victoria Tittle, Diarmuid Nugent2.
Sex Transm Infect. Epub ahead of print: (2021)
http://sti.bmj.com/cgi/content/full/sextrans-2021-055192?ijkey=9qNq9TcAOWPRo&keytype=ref&siteid=bmjjournals

High-throughput sequencing reveals dietary segregation in Malaysian babblers.
Mohammad Saiful Mansor, Fasihah Zarifah Rozali, Sian Davies, Shukor Md. Nor, Rosli Ramli
Current Zoology, 2021, https://doi.org/10.1093/cz/zoab074

Loss of Factor H family proteins associates with meningococcal disease severity.
Anna E. van Richard B. Pouw, Victoria J. Wright, Neneh Sallah, David Inwald, Clive Hoggart, Mieke C. Brouwer, Rachel Galassini, John Thomas, Leo Calvo-Bado, Colin Fink , Ilse Jongerius, Martin Hibberd, Diana Wouters, Michael Levin, Taco W. Kuijpers.
doi: https://doi.org/10.1101/2021.02.05.21251142

Biomarkers for the discrimination of acute Kawasaki disease from infections in childhood.
Judith Zandstra* , Annemarie van de Geer, Michael W.T. Tanck, Diana van Stijn-Bringas Dimitriades, Cathelijn Aarts, Sanne M Dietz, Robin Van Bruggen, Nina Schweintzger, Werner Zenz, Marieke Emonts, Dace Zavadska, Marko Pokorn, Effua Usuf, Henriette Moll, Luregn J Schlapbach, Enitan Carrol, Stephane Christian Paulus, Maria Tsolia, Colin Fink, Shunmay Yeung, Chisato Shimizu, Adriana Tremoulet, Rachel Galassini, Victoria J Wright, Federico Martinon-Torres, Jethro Herberg, Jane Cary Burns, Michael L Levin and Taco W Kuijpers
Original Research, Front. Pediatr. - Pediatric Immunology 2020

Molecular detection of SARS-CoV-2 using a reagent-free approach.
Calvez R, Taylor A, Calvo-Bado L, Fraser D, Fink CG.
PLoS One. 2020 Dec 7;15(12):e0243266 10.1371/journal.pone.0243266

Phenotypic variation and polymorphism confirmed among white-bellied swiftlets of the Collocalia esculenta group (Apodidae, Collocaliini) by mitochondrial and nuclear DNA evidence.
Sian E W Davies, Wei Lim Goh, Sarah P Ball, Earl of Cranbrook, Wei Sheng Siew and Michael Tarburton.
Bulletin of the British Ornithologists’ Club (Bull. B.O.C.) 2020 140(4) https://doi.org/10.25226/bboc.v140i4.2020.a2

Ancient microRNA profiles of a 14,300-year-old canid samples confirm taxonomic origin and give glimpses into tissue-specific gene regulation from the Pleistocene.
Bastian Fromm, Marcel Tarbier, Oliver Smith, Emilio Marmol-Sanchez, Love Dalen, Tom P Gilbert, & Marc R Friedlander.
RNA, doi: 10.1261/rna.078410.120, 2020

AMY1 Gene Copy number Correlates with Glucose Absorption and Visceral Fat Volume, but Not with Insulin Resistance.
Thomas M Barber, Ahsan A Bhatti, Patrick JD Elder, Sarah P Ball, Ronan Calvez , David B Ramsden, Dan J Cuthbertson, Andreas F Pfeiffer, David Burnett and Martin O Weickert.
Journal of Clinical Endocrinology and Metabolism. 2020 105. e3586-e3596 https://doi.org/10.1210/clinem/dgaa473

Asymptomatic Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in a Rehabilitation Facility: Evolution of the Presence of Nasopharyngeal SARS-CoV-2 and Serological Antibody Responses.
Benjamin H. L. Harris, Mohamed Zuhair, Matteo Di Giovannantonio, Carolina Rosadas, Maryam Khan, Charlotte-Eve Short, Thilipan Thaventhiran, Rachael Quinlan, Andrew Taylor, Ronan Calvez, Graham P. Taylor, Richard S. Tedder, Myra O. McClure, and Michael Fertleman.
The Journal of Infectious Diseases https://doi.org/10.1093/infdis/jiaa610, 2020

Hi-C chromosome conformation capture sequencing of avian genomes using the BGISEQ-500 platform.
Marcela Sandoval-Velasco, Juan Antonio Rodríguez, Cynthia Perez Estrada, Guojie Zhang, Erez Lieberman Aiden, Marc A Marti-Renom, M Thomas P Gilbert & Oliver Smith.
GigaScience 9 (8), doi: 10.1093/gigascience/giaa087, 2020

The secrets of Sobek – A crocodile mummy mitogenome from ancient Egypt.
Evon R. Hekkala, Matthew L. Aardema, Apurva Narechania, George Amato, Salima Ikram, Matthew H. Shirley, Kent A. Vliet, Seth W. Cunningham, M. Thomas P. Gilbert, Oliver Smith.
Journal of Archaeological Science: Reports 33, doi: 10.1016/j.jasrep.2020.102483

PIA: More Accurate Taxonomic Assignment of Metagenomic Data Demonstrated on sedaDNA From the North Sea.
Cribdon B, Ware R, Smith O, Gaffney V and Allaby RG (2020).
Front. Ecol. Evol. 8:84. doi:10.3389/fevo.2020.0084

Viral and bacterial infection elicit distinct changes in plasma lipids in febrile children.
Xinzhu Wang, Ruud Nijman, Stephane Camuzeaux, Caroline Sands, Heather Jackson, Myrsini Kaforou, Marieke Emonts, Jethro Herberg, Ian Maconochie, Enitan D Carrol, Stephane C Paulus, Werner Zenz, Michiel Van der Flier, Ronald de Groot, Federico Martinon-Torres, Luregn J Schlapbach, Andrew J Pollard, Colin Fink, Taco T Kuijpers, Suzanne Anderson, Matthew Lewis, Michael Levin, Myra McClure, on behalf of EUCLIDS consortium (2019).
doi: https://doi.org/10.1101/655704 I Open access reports Nature

Temporal association of the development of oropharyngeal microbiota with early life wheeze in a population based birth cohort.
Elizabeth Powell, Sara Fontanella, Eve Boakes, Daniella Belgrave, Alex G Shaw, Emma Cornwell, Roberto Fernandez-Crespo, Colin G Fink, Adnan Custovic, J Simon Kroll.
E-Bio-Medicine 46 pp486-498 2019

Identification of regulatory variants associated with genetic susceptibility to meningococcal disease.
Borghini L, Png E, Binder A, Wright VJ, Pinnock E, de Groot R, Hazelzet J, Emonts M, Van der Flier M, Schlapbach LJ, Anderson S, Secka F, Salas A, Fink C, Carrol ED, Pollard AJ, Coin LJ, Kuijpers TW, Martinon-Torres F, Zenz W, Levin M, Hibberd ML, Davila S; EUCLIDS consortium.
Sci Rep. 2019 May 6;9(1):6966. doi: 10.1038/s41598-019-43292-6.

In Response to: Smit D, Meyer D, Maritz J, et al. "Polymerase Chain Reaction and Goldmann-Witmer Coefficient to Examine the Role of Epstein-Barr Virus in Uveitis".
Murray PI, Fink C, Trivedi D.
Ocul Immunol Inflamm. 2019;27(1):114-115. doi: 10.1080/09273948.2017.1400075. Epub 2017 Nov 30. No abstract available.

Cytomegalovirus infection is not a major cause of corneal graft failure in the United Kingdom.
da Costa Paula CA, Gore DM, Shah K, Kuit G, Angunawela RI, Barnett JP, and Tuft SJ. (2019).
Eye 33, 833-837.

Human Amylase gene copy number variation as a determinant of metabolic state.
Elder J.D., Ramsden D.B., Burnett D., Weickert M.O., Barber T.
Expert review of Endocrinology and Metabolism. 2018 (13) 193-205

Life-threatening infections in children in Europe (the EUCLIDS Project): a prospective cohort study.
Boeddha NP, Klobassa DS, Secka F, Paulus S, de Groot R, Schlapbach LJ, Driessen GJ, Anderson ST, Emonts M, Zenz W, Carrol ED, Van der Flier M, Levin M; EUCLIDS Consortium.
Lancet Child Adolesc Health. 2018 Jun;2(6):404-414. doi: 10.1016/S2352-4642(18)30113-5. Epub 2018 Apr 28.

Genetic diversity among white-nest swiftlets of the genus Aerodramus (Aves: Apodidae: Collocaliini) of house-farms in Malaysia.
Goh W.L., Siew W.S., Davies S.E.W., Ball S., Khoo G., Lim C.K., Rahman M. A., Earl of Cranbrook.
Raffles Bulletin of Zoology. 2018 June 22; (66):350–360

Mortality and morbidity in community-acquired sepsis in European paediatric intensive care units: a prospective cohort study from the European Childhood Life-threatening Infectious Disease Study (EUCLIDS).
Boeddha NP, Schlapbach LJ, Driessen GJ, Herberg JA, Rivero-Calle I, Cebey-López M, Klobassa DS, Philipsen R, de Groot R, Inwald DP, Nadel S, Paulus S, Pinnock E, Secka F, Anderson ST, Agbeko RS, Berger C, Fink CG, Carrol ED, Zenz W, Levin M, van der Flier M, Martinón-Torres F, Hazelzet JA, Emonts M; EUCLIDS consortium.
Crit Care. 2018 May 31;22(1):143. doi: 10.1186/s13054-018-2052-7.

Comparison of the first whole genome sequence of Haemophilus quentini with two new strains of Haemophilus quentini and other species of Haemophilus.
Hubbard A.T.M, Davies S.E.W., Baxter L., Thompson S, Collery M.M, Hand D.C, Thomas D.J .I, Fink C.G
Genome. 2018 May;61 (5):379-385. doi: 10.1139/gen-2017-0195. Epub 2018 Mar 13

Diagnostic Test Accuracy of a 2-Transcript Host RNA Signature for Discriminating Bacterial vs Viral Infection in Febrile Children.
Herberg JA, Kaforou M, Wright VJ, Shailes H, Eleftherohorinou H, Hoggart CJ, Cebey-López M, Carter MJ, Janes VA, Gormley S, Shimizu C, Tremoulet AH, Barendregt AM, Salas A, Kanegaye J, Pollard AJ, Faust SN, Patel S, Kuijpers T, Martinón-Torres F, Burns JC, Coin LJ, Levin M; IRIS Consortium.

Collaborators:Carter MJ, Coin LJ, Eleftherohorinou H, Fitzgerald E, Gormley S, Herberg JA, Hoggart C, Inwald D, Janes VA, Jones KD, Kaforou M, Mustafa S, Nadel S, Paulus S, Pathan N, Reid J, Shailes H, Wright VJ, Levin M, Faust S, McCorkill J, Patel S, Pollard AJ, Willis L, Young Z, Fink C, Sumner E, Kanegaye JT, Shimizu C, Tremoulet A, Burns J, Cebey-López M, Salas A, Grande AJ, Rivero I, Carballa AG, Seco JP, Sánchez JM, Collazo LR, Rodríguez-Tenreiro C, Trillo LV, Martinón-Torres F, Barendregt AM, van den Berg M, Schonenberg D, Kuijpers T, Hibberd ML, Emonts M.
JAMA. 2016 Aug 23-30;316(8):835-45.

Does Viral Co-Infection Influence the Severity of Acute Respiratory Infection in Children?
Cebey-López M, Herberg J, Pardo-Seco J, Gómez-Carballa A, Martinón-Torres N, Salas A, Martinón-Sánchez JM, Justicia A, Rivero-Calle I, Sumner E, Fink C, Martinón-Torres F; GENDRES network.
PLoS One. 2016 Apr 20;11(4):e0152481. doi: 10.1371.

Draft whole-genome sequence of a Haemophilus quentini strain isolated from an infant in the United Kingdom.
Hubbard ATM, Davies SEW, Baxter L, Thompson S, Collery MM , Hand DC, Fink CG, Thomas DJI.
2016. Genome Announc 4(5):e01075-16. doi:10.1128/genomeA.01075-16

Bacteremia in Children Hospitalized with Respiratory Syncytial Virus Infection.
Miriam Cebey-López, Jacobo Pardo-Seco1,, Alberto Gómez-Carballa, Nazareth Martinón-Torres, José María Martinón-Sánchez, Antonio Justicia-Grande, Irene Rivero-Calle, Elli Pinnock, Antonio Salas, Colin Fink, Federico Martinón- Torres1, GENDRES network
Plos One open access February (2016).

Viral Co-Infections in Pediatric Patients Hospitalized with Lower Tract Acute Respiratory Infections.
Miriam Cebey-López, Jethro Herberg, Jacobo Pardo-Seco, Alberto Gómez-Carballa, Nazareth Martinón-Torres, Antonio Salas, José María Martinón-Sánchez, Stuart Gormley, Edward Sumner , Colin Fink, Federico Martinón-Torres, GENDRES network
Plos One Published on line September 2nd 2015 DOI: 10.1371/journal.pone.0136526.

New Approaches to the understanding of ’Infection‘
Chapter In Current Progress in Obstetrics and Gynaecology
Fink, C.G, and Pinnock Eleanor
Editor John. Studd, Seang Lin Tang, Frank A Chervenak
Publishers Tree Life Medical Kothari Medical India (2014)

2013, Transcriptomic Profiling in Childhood H1N1/09 Influenza Reveals Reduced Expression of Protein Synthesis Genes.
Herberg JA, Kaforou M, Gormley S, Sumner ER, Patel S, Jones KDJ, Paulus S, Fink C , Martinon-Torres F, Montana G, Wright VJ, Levin Met al.
J. INF DIS, Vol: 208, Pages: 1664-1668.

DNA analysis of skeletal tissue recovered from the English Channel 2013.
J Fredericks, K Brown, A Williams, P Bennett
J Foren & Legal Med August Vol: 20, Pages 757–759.

Whole genome pyrosequencing of rare hepatitis C virus genotypes enhances subtype classification and identification of naturally occurring drug resistance variants.
Newman RM, Kuntzen T, Weiner B, Berical A, Charlebois P, Kuiken C, Murphy DG, Simmonds P, Bennett P , Lennon NJ, Birren BW, Zody MC, Allen TM, Henn MR.
(2013) J Infect Dis. 208(1):17-31

Characterization of full-length HCV sequences for subtypes 1e, 1h, and 1l, and a novel variant revealed Cameroon as an area in origin for genotype 1.
Li C, Njouom R, Pépin J, Nakano T, Bennett P, Pybus OG, Lu L.
(2013) J Gen Virol. 2013 May 15. [Epub ahead of print]

FTIR spectroscopy: A new diagnostic tool to aid DNA analysis from heated bone.
Fredericks JD, Bennett P, Williams A, Rogers KD.
Forensic Sci Int Genet. 2012 May;6(3):375-80. Epub 2011 Oct 2

A novel multilocus sequence typing scheme for the opportunistic pathogen Propionibacterium acnes and characterization of type I cell surface-associated antigens.
McDowell A, Gao A, Barnard E, Fink C, Murray PI, Dowson CG, Nagy I, Lambert PA, Patrick S.
Microbiology. 2011 Jul;157(Pt 7):1990-2003. Epub 2011 Apr 21.

Pneumocystis jirovecii, Mycoplasme pneumoniae and Chlamydia pneumoniae carriage rates in adult cystic fibrosis patients in West Midlands, England
R. Rashid, J. C. Brown, J. Whitehouse, N. Edward, C. G. Fink, C. G. Dowson, D. Honeybourne
Jun 2011, Journal of Cystic Fibrosis

A Novel Hemotropic Mycoplasma (Hemoplasma) in a Patient With Hemolytic Anemia and Pyrexia.
Jane A. Steer, Séverine Tasker, Emily N. Barker, Jørgen Jensen, Joanne Mitchell, Teresa Stocki, Victoria J. Chalker, and Mike Hamon
(2011) Clin Infect Dis. 53(11): e147-e151

VenUS II: a randomised controlled trial of larval therapy in the management of leg ulcers.
J Dumville, G Worthy, M Soares, J Bland, N Cullum, C Dowson, C Iglesias, D McCaughan, J Mitchell , E Nelson, and D Torgerson
(2009) Health Technol Assess. 13(55):1-206

Complete genomic sequences for hepatitis C virus subtypes 4b, 4c, 4d, 4g, 4k, 4l, 4m, 4n, 4o, 4p, 4q, 4r and 4t.
Li C, Lu L, Wu X, Wang C, Bennett P, Lu T, Murphy D.
(2009) J Gen Virol. 90(Pt 8):1820-6.

Larval therapy for ulcers (VenUS II): a randomised controlled trial.
Jo C Dumville, Gill Worthy, John Martin Bland, Nicky A Cullum, Christopher Dowson, Cynthia P Iglesias, Joanne L Mitchell, E Andrea Nelson, Marta Soares, and David J Torgerson
(2009) Brit Med J; 338:b773

A set of reference sequences for the hepatitis C genotypes 4d, 4f, and 4k covering the full open reading frame.
Kuntzen T, Berical A, Ndjomou J, Bennett P, Schneidewind A, Lennon N, Birren BW, Kuiken C, Henn MR, Simmonds P, Allen TM.
(2008) J Med Virol. 80(8):1370-8

Characterization of tRNA-dependent peptide bond formation by MurM in the synthesis of Streptococcus pneumoniae peptidoglycan.
Lloyd AJ, Gilbey AM, Blewett AM, Pascale GD, Zoeiby AE, Levesque RC, Catherwood AC, Tomasz A, Bugg TD, Roper DI, Dowson CG.
(2007) J Biol Chem. Dec 12; [Epub ahead of print]

Adaptation to human populations is revealed by within-host polymorphisms in HIV-1 and hepatitis C virus.
Poon AF, Kosakovsky Pond SL, Bennett P, Richman DD, Leigh Brown AJ, Frost SD.
(2007) PLoS Pathog. 3(3):e45.

Proinflammatory activation of Toll-like receptor-2 during exposure of penicillin resistant Streptococcus pneumoniae to ß-lactam antibiotics.
Moore L, Gilbey A, Dowson C, Pridmore A, Dower S, Read R.
(2007) J Antimicrob Chemother. 59(1):35-42

Incremental increase in fitness cost with increased beta -lactam resistance in pneumococci evaluated by competition in an infant rat nasal colonization model.
Trzcinski K, Thompson CM, Gilbey AM, Dowson CG, Lipsitch M.
(2006) J Infect Dis. 1;193(9):1296-303

Adenovirus type F subtype 41 causing disseminated disease following bone marrow transplantation for immunodeficiency.
Slatter MA, Read S, Taylor CE, Crooks BN, Abinun M, Flood TJ, Cant AJ, Wright C, Gennery AR.
(2005) J Clin Microbiol. 43(3):1462-4

Virus DNA Quantification: An Adjunctive Diagnostic Marker for AIDS-Associated Lymphoma.
Ho SF, Fink C, Murray PI.
(2005) Epstein-Barr Ocul Immunol Inflamm. 13(6):471-3

Phospho-N-acetyl-muramyl-pentapeptide translocase from Escherichia coli: catalytic role of conserved aspartic acid residues.
Lloyd AJ, Brandish PE, Gilbey AM, Bugg TD.
(2004) J Bacteriol. 186(6):1747-57

The Detection of Circulating Breast Cancer Cells in Blood.
Gilbey A.M., Burnett .D., Coleman R.E., Holen I.
(2004) Journal of Clinical Pathology; 57:903-911

Diagnostic molecular microbiology for the gynaecologist. In: Progress in Obstetrics and Gynaecology.
Fink C.G.
(2003) Ed: John Studd. Publ. Churchill Livingstone, Edinburgh. Volume 15. pp153-168

DNA Sequencing and the Human Genome Project. In: Molecular Biology in Cellular Pathology.
Bennett P.
(2003) Eds: J. Crocker, P.G. Murray. Publ. John Wiley & Sons Ltd, Chicester, UK

Classification of bacteria responsible for ENT and eye infections using the cyranose system.
Boilot, P.; Hines, E.L.; Gardner, J.W.; Pitt, R.; John, S.; Mitchell, J.; Morgan, D.W.
(2002) IEEE Sensors Journal; 2(3):247-253

Molecular Microbiology for the Ophthalmologist.
Fink C.G. and Butler L.
(2002) Eye News 9(3):54-61

Expression and activity of ADAMST-5 in synovium.
Vankemmelbeke MN, Holen I, Wilson AG, Ilic MZ, Handley CJ, Kelner GS, Clark M, Liu C, Maki RA, Burnett D, Buttle DJ.
(2001) European Journal of Biochemistry; 268: 1259-1268

LightCycler multiplex PCR for the laboratory diagnosis of common viral infections of the central nervous system.
Read S.J., Mitchell J.L., and Fink C.G.
(2001) Journal of Clinical Microbiology; 39(9):3056-3059

Recovery efficiencies of nucleic acid extraction kits as measured by quantitative LightCycler PCR.
Read S.J.
(2001) Journal of Clinical Pathology;Molecular Pathology; 54: 86-90

The Inflammatory Response. In: The Biology of Disease.
Burnett D. and Kirk P.
(2001) Publ. Blackwell Science, Oxford. 2nd Edition. pp39-48

Molecular techniques for clinical diagnostic virology.
Read S.J., Burnett D. and Fink C.G.
(2000) Journal of Clinical Pathology; 53: 502-506

Ophthalmic Zoster sine Herpete.
Goon P., M. Wright and C.G. Fink
(2000) Case report: Journal of the Royal Society of Medicine; 93: 191-192

Polymerase chain reaction for the laboratory diagnosis of aseptic meningitis and encephalitis.
Chesky M., Scalco R., Failace L., Read S.J., Jobim L.F.
(2000) Arquivos de Neuro Psiquiatria; 58: 836-842

The Immune Response to Haemophilus Parainfluenzae in Patients with Chronic Lung Disease.
Mitchell J.L. and Hill S.L.
(2000) Clinical and Diagnostic Laboratory Immunology; 7:25-30

Laboratory diagnosis of common viral infections of the central nervous system by using a single multiplex PCR screening assay.
Read S.J. and J.B. Kurtz
(1999) Journal of Clinical Microbiology: 37: 1352-1355

Viral CNS infections – diagnostic strategies.
Read S.J.
(1999) Proceedings of the 9th European Congress of Clinical Microbiology and Infectious Diseases, Berlin

A direct correlation between nicotinamide N-methyltransferase activity and protein levels in human liver cytosol.
Smith M-L., D. Burnett, P. Bennett, R.H. Waring, H.M. Brown, A. C. Williams and D.B. Ramsden
(1998) Biochimica et Biophysica Acta; 1422:238-244

Cleavage of native type 1 collagen by human neutrophil elastase.
Kafienah W., D. J. Buttle, D. Burnett and A. P. Hollander
(1998) Biochemical Journal; 330:897-902

Protein Assays In: The Science of Laboratory Diagnosis.
Burnett D. Eds: Crocker J. and Burnett D.
(1998) Isis Medical Media. Oxford. 461-470

The Science of Laboratory Diagnosis.
Crocker J. and Burnett D. (Eds)
(1998) Publ. Isis Medical Media. Oxford

Neutrophils. In Pulmonary Defences.
Burnett D; Ed R.A. Stockley
(1997) John Wiley

The Toxoplasmosis Test – Why All Women Should be Screened.
Fink C.G.
(1996) Pregnancy and Birth; June: 58-61

Toxoplasmosis Infection – A General Practitioners Update.
Fink C.G.
(1996) Pulse; 56:78-79

Inflammation. In: The Biology of Disease.
Burnett D. Eds: Phillips J, Murray P.

(1995) Blackwell Scientific Publications Oxford. pp22-30

Neurological Lesions Associated with Mycoplasma Pneumoniae Infection. PCR evidence against a direct invasive mechanism.
Fink C.G., M. Sillis, S.J. Read, L. Butler, M. Pike
(1995) Molecular Pathology; 48: M51-M54.