Ronan Calvez graduated from the University of Huddersfield in 1998 with a BSc (Hons) in Molecular and Cellular Biology, which was followed by an MSc in Biotechnologies at the University of Nottingham in 1999. He then obtained a PhD in Biochemistry at the University of Fribourg, Switzerland, in 2005 where he worked on the role of the PI3-Kinase gamma isoform in inflammation. Using a mouse model where this signalling molecule had been knocked out, he and his colleagues validated this specific signalling molecule as a potential therapeutic target in the treatment of some inflammatory diseases.
After completing his PhD, he worked as a Marie Curie-funded postdoctoral scientist for 4 years in the team of Loic Dupre and Salvatore Valitutti in Toulouse (INSERM). His research project aimed at better understanding a rare immune deficiency, the Wiskott Aldrich syndrome (WAS). His project involved the generation of different human cellular models reproducing the disease in-vitro, and then the development and validation of various functional assays to better characterise the defects observed in-vivo, using a wide array of technologies and imaging tools, such as 3D and 4D confocal microscopy, flow cytometry and molecular biology.
In 2010, Ronan joined a flow cytometry instrument company, Accuri Cytometers, where he worked as a technical application specialist to support customers all over Europe.
Ronan joined Micropathology in June 2012 as a postdoctoral scientist where he will be involved in the company’s molecular diagnostic work and in assay validation.