Dr Michael Steele studied for a BSc (Hons) at the University of Leicester, graduating in 2012. During this time, he undertook a summer project on mycobacterial antibiotic resistance and a final year project working on auto-transported proteins in Burkholderia. After this, Michael completed a PhD at the University of Exeter, supervised by Dr Claudia Hemsley, Professor Rick Titball, and Dr Helen Atkins at the Defence Science and Technology Laboratory (DSTL). His project studied persister cells, which are resistant to killing by antibiotics due to changes in their metabolism, with a view to improving the effectiveness of antibiotics against chronic and recurrent diseases. Persister formation and antibiotic tolerance were investigated in Burkholderia thailandensis as a representative model for the melioidosis-causing strain Burkholderia pseudomallei, using both phenotypic and genotypic methods.
Michael joined Micropathology in January 2019 and will be working in the microbiology diagnostic team as a postdoctoral scientist.