SPECIMEN TYPES RECOMMENDED FOR OPTIMAL TEST PERFORMANCE


Please note, the following list is for guidance only and is not intended to be exhaustive. We accept and test many different kinds of clinical sample including tissue samples. If you are unsure of the appropriateness of a particular sample, please contact us before sending it. Please also note the following points.

TARGET
PREFERRED SAMPLE
Blood-borne viral infections

HCV and HBV (including detection, quantitation, genotyping & resistance screening)

Plasma or serum
HIV-1 proviral DNA or RNA (i.e. for primary diagnosis) EDTA whole blood
HIV-1 RNA Quantitation Blood should be taken into EDTA tubes. The plasma should be separated within 6 hours of blood collection and shipped at room temperature for next day delivery.
HIV-1 Anti-Retroviral drug resistance screening
Blood should be taken into EDTA tubes. The plasma should be separated within 2 hours of blood collection and shipped at room temperature for next day delivery.
Respiratory infections
Respiratory viruses or bacteria
Any respiratory specimen is acceptable e.g. sputum, BAL, NPA, nasopharyngeal swab etc.
Genitourinary infections
Chlamydia/gonococcus (female)
Endocervical swab + first pass urine*
Chlamydia/gonococcus (male)
Urethral swab + first pass urine*
*We will process specimens together as one for economy: the two separate sites of sampling increase the sensitivity of the test. We will also accept single samples.
Chlamydia/gonococcus and HPV
Endocervical swab sent in plain tube or ‘thin prep’ endocervical cellular specimens#
#We are also able to arrange cytological preparation and review of thin preps. Please contact us about this service.
Herpes simplex infection
Endocervical or vulval lesions: rub a dry swab over the area and return it to a plain DRY holder
Infections associated with post-transplant or immunocompromised patients
CMV or EBV DNA viral load
EDTA whole blood or serum (plain or gel tube). EDTA is ideal but serum will be acceptable.
Adenovirus (quantitation)
EDTA whole blood
Adenovirus (detection and genotyping)
Any appropriate sample (please contact us if unsure)
Polyoma BK
EDTA whole blood or urine
Polyoma JC
EDTA whole blood, CSF or urine
Infections important in pregnancy
Parvovirus
EDTA whole blood, amniotic fluid
Toxoplasma
EDTA whole blood, amniotic fluid
CMV
EDTA whole blood, amniotic fluid, cervical swab
Rubella
EDTA whole blood, serum (for antibodies)
Measles
EDTA whole blood, serum, urine, saliva, nasopharyngeal swab
HSV
Vulval/vaginal swab
Intracellular organisms
Tropheryma whippelii
Almost any cellular material is acceptable including EDTA whole blood. PLEASE DO NOT SEND SERUM.
Mycobacterium tuberculosis complex